Endocrine Abstracts

IntroductionThe insulin tolerance test (ITT) is the gold standard for the assessment of the integrity of the hyopothalamo-pituitray adrenal axis. it’s major drawbacks are the mandatory presence of an experienced physician and continuous supervision to detect any complication. Our study aims to evaluate the indications and the outcomes of the ITT performed in our department.Patients and methodsWe conducte...

IntroductionFahr’s syndrome (FS) is a rare neurodegenerative disorder. It’s characterized by abnormal calcifications in basal ganglia and cerebral cortex inducing neuropsychiatric disorders and cognitive impairment. The aim of our study was to assess the prevalence of FS, its characteristics, and its associated factors in patients with permanent hypoparathyroidism.MethodsWe conducted a cross-section...

IntroductionHomeostasis model assessment for insulin resistance (HOMA-IR) is widely used as a marker of insulin resistance. However, it reminds an expensive maker requiring insulin dosage. Several studies tried to found simple alternative predictors of insulin resistance such as triglycerides to HDL-C ratio with conflicting reported findings. The aim of our study was to investigate the usefulness of the atherogenic index of plasma (AIP) and the visceral ...

IntroductionNasopharyngeal carcinoma is characterized by distinct geographical distribution and is particularly prevalent in East and Southeast Asia. Environmental factors, genetic structure, and Epstein Barr virus infection are involved in the etiology of the disease. While nasal and otological symptoms are the most common (80%), intracranial extension is prevalent among 8% of cases and pituitary localization is rarely described in the literature. We re...

IntroductionPrimary mediastinal goiter is an extremely uncommon entity. The majority of primary mediastinal goiters were reported as incidental findings on chest imaging of asymptomatic patients. Symptoms related to compression of adjacent structures and hyperthyroidism were rarely described. Herein we report a case of subclinical hyperthyroidism secondary to a primary mediastinal goiter.ObservationA 50 year-...

Hashimoto’s thyroiditis (HT) is a chronic disease that needs a daily substitution by thyroid hormones. The purpose of this study was to assess the level of therapeutic adherence to the hormonal treatment in HT patients and its impact on the thyroid function control.MethodsIt is a cross sectional study including 43 patients treated for hypothyroid Hashimoto’s thyroiditis by levothyroxine (LT4). The patient adherence to tre...

IntroductionGraves orbitopathy is the main extra thyroidal manifestation of Graves’ disease, though severe forms are rare (< 5%). Management of Graves orbitopathy is often suboptimal, largely because available treatments do not target pathogenic mechanisms of the disease. The aim of our study was to evaluate different treatment modalities and assess their impact on the outcome of Graves orbitopathy.Patients and methods...

IntroductionPsychological disorders may be expected in patients with hyperprolactinemia. Indeed, they generally have poor quality of life, anxiety, depression and certain personality troubles. Dopamine agonists are the first-line treatment of prolactinoma. Recently, an increasing number of reports emphasized on dopamine agonists psychological side effects. Effectively, some patients develop de novo psychiatric symptoms or have exacerbation of pre-existin...

Gender is a factor in clinical presentation, biological and morphological characteristics in certain types of pituitary adenomas. Concerning acromegaly, this influence is not well known. In our retrospective study of 32 patients, 12 women and 20 men, hospitalized in our department from 2002 to 2019, we have realized a comparative clinical, para-clinical, therapeutic and prognosis. The median age of women is 47 years, the same as that of men. The average duration of disease pro...

IntroductionAcromegaly is a rare chronic disorder caused by GH hypersecretion. It’s associated with an elevated morbidity and mortality rate. Cardiovascular diseases’ complications are the first cause of mortality in patients. In this study we conducted an assessement of cardivascular risk factors in patients with acromegaly.Patients and methodsA retrospective evaluative study of 32 patients followe...